Results: PASH was identified in 579 of 9065 biopsies (6.4%).
Pseudoangiomatous stromal hyperplasia (PASH) is a benign disease of the breast characterized by a complex network of slitlike spaces lined by slender spindle cells within a background of stromal hyperplasia [] (Figs. PASH is a rare condition. Healthline Media does not provide medical advice, diagnosis, or treatment. Don’t routinely excise areas of psuedoangiomatous stromal hyperplasia (PASH) of the breast in patients who are not having symptoms from it. Because the condition can mimic breast cancer as well as noncancerous breast lumps like fibroadenomas, it needs investigation, evaluation, and follow-up. Level of validity is your personal judgment, not what others believe (or don’t believe) is important.
Acne, rosacea, and related disorders. However, it may also produce a mass lesion. This is a procedure, usually done using a local anesthetic to numb the area, in which a hollow needle is inserted into the breast to remove tissue for sampling. The sonographic feature is a hypoechoic mass. Smoking, excess weight and metabolic syndrome also might play a role. Bolognia JL, et al., eds. Use your non-Mayo Clinic apps. Deckers IE, et al.
To our knowledge, there are no reports on the use of tamoxifen or other selective estrogen receptor modulators in the management of this benign breast condition. Atypical hyperplasia is a precancerous condition that affects cells in the breast. To confirm the diagnosis, a biopsy is required primarily to distinguish PASH from a low-grade angiosarcoma. * The RAND/UCLA Appropriateness Method User’s Manual 2008. After reading about it, it makes sense why a post-menopausal woman of 55 has enlarging painful breasts, almost like PMS used to be. AB - Background: Pseudoangiomatous stromal hyperplasia (PASH) is a benign localized fibrotic lesion in which clusters of spindle cells form cleftlike spaces, resembling ectatic vessels. Lebwohl MG, et al. Log in to Your Patient Account New to online services? Conclusions: Despite clinical concern generated by palpable density often associated with PASH, this relatively uncommon histological finding does not connote increased risk of subsequent breast cancer. Interventions for hidradenitis suppurativa.
Incision and drainage. It most commonly occurs in the armpits (shown), groin, between the buttocks and under the breasts. Here's what you need to know about what you should do next.
Materials and Methods: Histological presence of PASH was evaluated by review of archival slides in a single institution cohort of women who underwent benign excisional breast biopsy from 1967 to 1991. The clinicopathologic spectrum of this disease entity can range from a focal nonsignificant microscopic finding to a dominant palpable breast mass. Make a donation. We're you planning breast reduction before getting the PASH diagnosis or is that part of treatment? After creation of a list of 28 candidate measures, two rounds of modified Delphi process ranking were performed electronically—October, 2016 and December, 2016—following the iterative and analytic methodology in the RAND UCLA Ranking manual.*.
Comment in Breast J. Patients with any specific questions about the items on this list or their individual situation should consult their physician.